Which of the following pollutants are responsible for depletion of ozone layer?

Chlorofluorocarbons (CFCs), used in refrigerators, air conditioners, and aerosol sprays, are the primary cause of ozone layer depletion. When CFCs reach the stratosphere, UV radiation breaks them down to release chlorine atoms, which catalytically destroy ozone molecules. Carbon dioxide and methane are greenhouse gases that contribute to global warming, not ozone depletion. Acid rain is caused by sulfur and nitrogen oxides.