Which of the following statements with regard to genetic medicine is/are correct? 1. Genetic medicines correct/compensate for the faulty genes responsible for disease. 2. Engineered viruses and lipid nanoparticles are used as carriers of the genetic medicine. 3. Genetic medicines alter the entire DNA sequence. Select the answer using the code given below:

Genetic medicines (gene therapies) work by correcting, replacing or compensating for faulty genes responsible for a disease — either by inserting a functional copy of a gene, silencing a malfunctioning gene, or editing the gene; hence statement 1 is correct. Delivery vectors include engineered viral vectors (such as adeno-associated viruses, lentiviruses) and non-viral carriers such as lipid nanoparticles (as used in mRNA vaccines), so statement 2 is correct. However, genetic medicines do NOT alter the entire DNA sequence of an organism; they target specific genes or specific sequences within the genome. Statement 3 is therefore incorrect. Hence statements 1 and 2 only are correct.